| Description |
xvi, 443 p., [12] p. of plates : ill. (some col.) |
| Bibliography |
Includes bibliographical references. |
| Contents |
The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins -- Separation based analytical methods for measuring protein aggregation -- Laser light scattering-based techniques used for the characterization of protein therapeutics -- Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals -- Analytical methods to measure sub-visible particulates -- Detection of visible particles in parenteral products -- Characterization of aggregates and particles using emerging techniques -- Ultraviolet absorption spectroscopy -- Fluorescence spectroscopy to characterize protein aggregates and particles -- Infrared spectroscopy to characterize protein aggregates -- Raman microscopy for characterization of particles -- Microscopic methods for particle characterization in protein pharmaceuticals -- Comparison of methods for soluble aggregate detection and size characterization -- Protein purification and its relation to protein aggregation and particles -- Formulation development and its relation to protein aggregation and particles. |
| Reproduction |
Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. |
| Subject |
Pharmaceutical chemistry.
|
|
Protein drugs -- Analysis.
|
| Added Author |
Mahler, Hanns-Christian.
|
|
Jiskoot, Wim.
|
|
ProQuest (Firm)
|
| ISBN |
9780470497180 (cloth) |
|
9781118150542 (e-book) |
| OCLC # |
EBC818481 |
|
