| Description |
1 online resource. |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Synthesis lectures on tissue engineering ; #9.
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| Bibliography |
Includes bibliographical references. |
| Note |
Title from PDF title page (Morgan & Claypool, viewed Oct. 8, 2012). |
| Contents |
1. Introduction -- 1.1 Cardiac tissue engineering -- 1.2 Objectives and scopes -- 1.3 Organization of the monograph -- Bibliography. |
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2. The heart, structure, cardiovascular diseases, and regeneration -- 2.1 Introduction -- 2.2 The heart and cardiac muscle structure -- 2.3 Myocardial infarction and heart failure -- 2.4 Cardiac extracellular matrix (ECM), its function and pathological changes after MI -- 2.5 Congenital heart defects -- 2.6 Endogenous myocardial regeneration -- 2.7 Potential therapeutic targets and strategies to induce myocardial regeneration -- Bibliography. |
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3. Cell sources for cardiac tissue engineering -- 3.1 Introduction -- 3.2 Sources for de novo cardiomyocytes for clinical applications -- 3.3 Contemporary alternatives, adult autologous stem and progenitor cells -- 3.4 Clinical trials and "paracrine effect" hypothesis of stem/progenitor cell transplantation -- 3.5 Summary and conclusions -- Bibliography. |
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4. Biomaterials, polymers, scaffolds, and basic design criteria -- 4.1 Introduction -- 4.2 Basic biomaterial design criteria -- 4.3 Biomaterial classification -- 4.4 Basic scaffold fabrication forms -- 4.5 Summary and conclusions -- Bibliography. |
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5. Biomaterials as vehicles for stem cell delivery and retention in the infarct -- 5.1 Introduction -- 5.2 Stem cell delivery by biomaterials -- 5.3 Clinical trials -- 5.4 Summary and conclusions -- Bibliography. |
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6. Bioengineering of cardiac patches, in vitro -- 6.1 Introduction -- 6.2 Cardiac cell entrapment in hydrogels, engineered heart tissue (EHT) -- 6.3 Cell sheet-based cardiac tissue engineering -- 6.4 Myocardial tissue grafts created in preformed implantable scaffolds -- 6.5 Biomimetic scaffolds and integration of cell-matrix interactions -- 6.6 Micro- and nanotechnology for scaffold fabrication -- 6.7 Summary and conclusions -- Bibliography. |
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7. Perfusion bioreactors and stimulation patterns in cardiac tissue engineering -- 7.1 Introduction -- 7.2 Bioreactor cultivation of engineered cardiac tissue -- 7.3 Inductive stimulation patterns in cardiac tissue engineering -- 7.4 Summary and conclusions -- Bibliography. |
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8. Vascularization of cardiac patches -- 8.1 Introduction -- 8.2 Prevascularization of the patch by incorporating endothelial cells (ECS) -- 8.3 The body as a bioreactor for patch vascularization -- 8.4 Summary and conclusions -- Bibliography. |
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9. Acellular biomaterials for cardiac repair -- 9.1 Introduction -- 9.2 Acellular implantable scaffolds for in situ tissue support -- 9.3 Decellularized ECM -- 9.4 Injectable biomaterials -- 9.5 First-in-man trial of intracoronary delivery of alginate biomaterial -- 9.6 Mechanism of biomaterial effects on cardiac repair -- 9.7 Immunomodulation of the macrophages by liposomes for infarct repair -- 9.8 Summary and conclusions -- Bibliography. |
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10. Biomaterial-based controlled delivery of bioactive molecules for myocardial regeneration -- 10.1 Introduction -- 10.2 Evolution of bioactive material approach for myocardial regeneration -- 10.3 Bioactive molecules for myocardial regeneration and repair -- 10.4 Scaffold- and hydrogel sheet-based molecule delivery -- 10.5 Injectable systems -- 10.6 Affinity-binding alginate biomaterial for multiple growth factor delivery -- 10.7 Summary and conclusions -- Bibliography -- Authors' biographies. |
| Reproduction |
Electronic reproduction. Perth, W.A. Available via World Wide Web. |
| Subject |
Heart.
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Tissue engineering.
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Heart -- Diseases.
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Myocardium -- Regeneration.
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affinity binding |
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alginate |
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biomaterials |
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biomimetic |
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cardiac tissue engineering |
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cardiac patches |
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cardiomyocytes |
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cell delivery |
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cell therapy |
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drug delivery |
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extracellular matrix |
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growth factors |
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heart |
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hydrogels |
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heart failure |
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immunomodulation |
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liposomes |
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myocardial infarction |
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myocardial regeneration |
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paracrine effect |
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perfusion bioreactors |
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scaffolds |
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stem cells |
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stimulation |
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vascularization |
| Added Author |
Sapir, Yulia.
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Cohen, Smadar, 1958-
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Ebooks Corporation
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| Related To |
Print version: 9781608452040 |
| ISBN |
9781608452057 (electronic bk.) |
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1608452050 (electronic bk.) |
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9781608452040 (paperback) |
| UPC # |
10.2200/S00437ED1V01Y201207TIS009 doi |
| OCLC # |
EBC967713 |
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