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Author Palsson, Bernhard.
Title Systems biology [electronic resource] : properties of reconstructed networks / Bernhard Ø. Palsson.
Publication Info. Cambridge ; New York : Cambridge University Press, 2006.
Location Call No. Status Notes
 Libraries Electronic Books  ELECTRONIC BOOK-Knovel    AVAIL. ONLINE
Description 1 online resource (xii, 322 p.) : ill.
Bibliography Includes bibliographical references (p. 299-315) and index.
Summary The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemistry.
Contents 1. Introduction -- 2. Basic concepts in systems biology -- 3. Metabolic networks -- 4. Transcriptional regulatory networks -- 5. Signaling networks -- 6. Basic features of the stoichiometric matrix -- 7. Topological properties -- 8. Fundamental subspaces of S -- 9. The (right) null space of S -- 10. The left null space of S -- 11. The row and column spaces of S -- 12. Dual causality -- 13. Properties of solution spaces -- 14. Sampling solution spaces -- 15. Finding functional states -- 16. Parametric sensitivity -- 17. Epilogue.
Subject Computational biology.
Genomics.
Bioinformatics.
Systems biology.
Systems Biology.
Related To Print version: Palsson, Bernhard. Systems biology. Cambridge ; New York : Cambridge University Press, 2006 0521859034 (DLC) 2005035008 (OCoLC)62421240
Standard No. 94940450 320227992 647503209 817928134
ISBN 0521859034
9780521859035
0511145128 (electronic bk. : Adobe Reader)
9780511145124 (electronic bk. : Adobe Reader)
1601197608 (electronic bk.)
9781601197603 (electronic bk.)
9780511790515 (electronic bk.)
0511790511 (electronic bk.)
Standard No. 9780521859035
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