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Author McEachron, D. L. (Donald L.)
Title Chronobioengineering [electronic resource] : introduction to biological rhythms with applications. Volume 1 / Donald McEachron.
Publication Info. [San Rafael, Calif.] : Morgan & Claypool Publishers, c2012.
Location Call No. Status Notes
 Libraries Electronic Books  ELECTRONIC BOOKS-DDA    AVAIL. ONLINE
Description 1 online resource.
Series Synthesis lectures on biomedical engineering ; # 43.
Bibliography Includes bibliographical references.
Contents Preface -- How to use this book -- Acknowledgments --
1. Time and time again -- 1.1 Timing is everything -- 1.2 An introduction to biological time -- 1.3 A preliminary case study -- 1.4 Why biological rhythms? -- 1.4.1 Temporal adaptation and the early bird -- 1.5 A conceptual model -- 1.6 A dynamic model -- 1.7 Rhythms and evolution -- 1.8 Chapter review -- References --
2. Walking on air: an empirical proof-of-concept -- 2.1 On the nature of scientific evidence -- 2.2 The evidence -- 2.2.1 On the nature of evolutionary processes -- 2.2.2 Observations on human subjects -- 2.3 Summary and conclusion for proposition 2.1 -- 2.4 Summary and conclusion for proposition 2.2 -- 2.4.1 Question 1. What is meant by the term "deleterious"? -- 2.4.2 Question 2. What is the nature of the evidence? -- 2.4.3 Question 3. What is the underlying nature of daily rhythm? -- 2.5 Chapter review -- References --
3. Clocktech, part 1 -- 3.1 Evolution of a mechanism -- 3.1.1 Environmentally driven rhythms -- 3.1.2 Are environmentally driven rhythms sufficient? -- 3.1.3 Limitations with environmentally driven rhythms and a new model -- 3.1.4 Multiple rhythms and phase relationships -- 3.1.5 Reaction vs. prediction in ecosystems and the new model -- 3.2 Chapter review -- References --
4. Clocktech II from external to internal timers -- 4.1 The cost and benefits of environmental drivers -- 4.2 A new dawn, internalizing the timers -- 4.3 Endogenous rhythms and biological clocks -- 4.3.1 Excitable tissue -- 4.4 A brief review -- 4.5 From rhythmic to autorhythmic: creating endogenous oscillators -- 4.6 Another brief review -- 4.7 Synchronizing endogenous rhythms to environmental cycles -- 4.8 The final analysis -- 4.9 Chapter review -- References --
5. Clocktech III, rise of the circarhythms -- 5.1 Starting forward by looking back -- 5.2 Circarhythms -- 5.3 Human studies -- 5.3.1 Travel across time zones, the phenomenon of "jet lag" -- 5.3.2 The 24/7 society, shiftwork, circadian disruption, and health issues -- 5.4 Animal studies -- 5.5 Summary and conclusion for proposition 2.3 -- 5.5.1 Measuring time's passing, the adaptive function of interval timers -- 5.6 Timing is (almost) everything -- 5.7 Overall conclusions -- References --
6. The circle game: mathematics, models, and rhythms -- 6.1 Introduction to mathematical modeling -- 6.2 Linear models of oscillators -- 6.3 Nonlinear models of oscillators -- 6.4 Modeling molecular networks in cells -- 6.5 Modeling external perturbations on biological oscillators: synchronization, entrainment, and other effects on rhythms -- 6.6 Phasic entrainment, parametric effects, and rhythm position -- 6.7 More detailed molecular network models -- 6.8 Conclusions and a caveat -- 6.9 Chapter review -- References -- 6.10 Additional reading -- More references --
7. The power of circular reasoning -- 7.1 Back to the future -- 7.2 A prototype investigative approach -- 7.2.1 Definitions and classifications -- 7.2.2 The complex case of the electroencephalogram (EEG) -- 7.2.3 The sensory-thalmacortical system -- 7.2.4 How neurons became rhythmic -- 7.2.5 Mode and level of rhythm generation of brain rhythms revisited -- 7.2.6 The in vitro evidence -- 7.2.7 Another slight digression: ionic currents and neural transmission -- 7.2.8 Relationship to electroencephalogram (EEG) -- 7.2.9 Models of oscillating neurons -- 7.2.10 Distance and lag time -- 7.3 Chapter review -- References --
A. Modeling approaches -- Modeling endocrine system using Matlab by Kevin Freedman -- Modeling neurons by Rajarshi Ganguly and George Neusch -- B. The end of the beginning -- Authors' biographies.
Reproduction Electronic reproduction. Perth, W.A. Available via World Wide Web.
Note Description based on online resource; title from digital title page (viewed on Mar. 08, 2013).
Subject Biological rhythms.
Biological rhythms -- Mathematical models.
Bioengineering.
biological rhythms
biological clocks
chronobiology
neural oscillators
physiological rhythms
mathematical modeling
feedback oscillation
Added Author Ebooks Corporation
Related To Print version: 9781598296358
ISBN 9781598296365 (electronic bk.)
1598296361 (electronic bk.)
9781598296358 (pbk.)
Standard No. 10.2200/S00446ED1V01Y201208BME043 doi
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