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Title Mass spectrometry for drug discovery and drug development [electronic resource] / edited by Walter A. Korfmacher.
Publication Info. Hoboken, N.J. : John Wiley & Sons, c2013.
Location Call No. Status Notes
 Libraries Electronic Books  ELECTRONIC BOOKS-DDA    AVAIL. ONLINE
Description 1 online resource.
Series Wiley-Interscience series on mass spectrometry.
Note Description based on print version record.
Bibliography Includes bibliographical references and index.
Contents 1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / GĂ©rard Hopfgartner -- 2. Utility of high-resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang -- 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia -- 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou -- 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash -- 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky -- 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak -- 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion -- 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendra N. Pramanik -- 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli -- 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer -- 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury -- 13. Mass spectrometry of siRNA / Mark T. Cancilla and W. Michael Flanagan -- 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily -- 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high-resolution full scan? / Lieve Dillen and Filip Cuyckens.
Reproduction Electronic reproduction. Perth, W.A. Available via World Wide Web.
Note Description based on print version record.
Subject Drugs -- Analysis.
Drug development.
Mass spectrometry.
Drug Discovery.
Mass Spectrometry -- methods.
Peptides -- analysis.
Pharmaceutical Preparations -- analysis.
Proteins -- analysis.
Added Author Korfmacher, Walter A.
Ebooks Corporation
Related To Original 9780470942383 047094238X (DLC) 2012031775
ISBN 9781118516126 (electronic bk.)
1118516125 (electronic bk.)
9780470942383 (cloth)
047094238X (cloth)
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