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Title Advances in DNA repair in cancer therapy [electronic resource] / Lawrence Panasci, Raquel Aloyz, Moulay Alaoui-Jamali, editors.
Publication Info. New York, NY : Humana Press, c2013.
Location Call No. Status Notes
 Libraries Electronic Books  ELECTRONIC BOOKS-DDA    AVAIL. ONLINE
Description 1 online resource.
Series Cancer drug discovery and development ; 72.
Bibliography Includes bibliographical references and index.
Contents Repair of DNA interstrand cross-links produced by cancer chemotherapeutic drugs -- DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy -- Growth factor receptor signaling, DNA damage response, and cancer cell susceptibility to chemotherapy and relapses -- Relationship between DNA-repair genes, cellular radiosensitivity, and the response of tumors annd normal tissues to radiotherapy -- Important roles of ERCCI in DNA repair and targeted therapy -- The role of BRCA1 and BRCA2 in anticancer drug therepy -- DNA-PK in CLL chemotherapy -- Poly (ADP) ribose polymerase at the interface of DNA damage signaling and DNA repair -- Cellular protection against the antitumor drug bleomycin -- ATR as a therapeutic target -- Telomores, Telomerase, and DNA damage response in cancer therapy -- RAD51 is a key protein of DNA repair and homologous recombination in humans.
Reproduction Electronic reproduction. Perth, W.A. Available via World Wide Web.
Subject DNA repair.
Cancer -- Chemotherapy.
Cancer -- Genetic aspects.
Cancer Research.
Molecular Medicine.
Added Author Panasci, Lawrence C.
Aloyz, Raquel.
Alaoui-Jamali, Moulay A.
Ebooks Corporation
ISBN 9781461447412 (electronic bk.)
1461447410 (electronic bk.)
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