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book jacket
Author Shargel, Leon, 1941-
Title Applied biopharmaceutics & pharmacokinetics [electronic resource] / Leon Shargel, Andrew B.C. Yu, Susanna Wu-Pong.
Publication Info. New York : McGraw-Hill, 2012.
Edition 6th ed.
Location Call No. Status Notes
 Libraries Electronic Books  ELECTRONIC BOOK-AccessPharmacy    AVAIL. ONLINE
Description p. ; cm.
Series AccessPharmacy
Bibliography Includes bibliographical references and index.
Contents Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.
Access License restrictions may limit access.
Subject Biopharmaceutics.
Models, Chemical.
Added Author Yu, Andrew B. C., 1945-
Wu-Pong, Susanna.
Note Applied biopharmaceutics and pharmacokinetics
ISBN 9780071603935 (hardcover : alk. paper)
007160393X (hardcover : alk. paper)
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